Delayed Rectification and Anomalous Rectification in Skeletal Muscle Membrane
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چکیده
منابع مشابه
Delayed Rectification and Anomalous Rectification in Frog's Skeletal Muscle Membrane
Delayed rectification was elicited in frog's skeletal muscles bathed in choline-Ringer's solution, in normal Ringer's solution with tetrodotoxin, in 40 mM Na(2)SO(4) solution with tetrodotoxin, and even in 40 mM K(2)SO(4) solution when the membrane had been previously hyperpolarized. However, after a sustained depolarization current-voltage relations in 40 mM K(2)SO(4) and in 40 mM Na(2)SO(4) s...
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Tetanic stimulation of skeletal muscle fibers elicits a train of spikes followed by a long-lasting depolarization called the late after-potential (LAP). We have conducted experiments to determine the origin of the LAP. Isolated single muscle fibers were treated with a high potassium solution (5 mM or 10 mM K) followed by a sudden reduction of potassium concentration to 2.5 mM. This procedure pr...
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NARAHASHI, TOSHIO, TAKEHIKO DEGUCHI, NORIMOTO URAKAWA AND YOSHIO OHKUBO. Stabilisation and rectijication of muscle jber membrane by tetrodotoxin. Am. J. Physiol. I $3 (5) : 934-938. 1g6o.-The mode of action of tetrodotoxin on the frog muscle fiber membrane has been analyzed with the aid of intracellular microelectrodes. Tetrodotoxin of I oH7 concentration made the applied cathodal current ineff...
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Delayed and anomalous rectification was studied in inferior olivary (I.O.) neurons in guinea pig brain stem slices maintained in vitro. Hyperpolarization of the I.O. cell beyond rest membrane potential was accompanied by anomalous rectification (AR). This consisted of 2 parts: an instantaneous and a time-dependent component. The "instantaneous" component was blocked by bath addition of Ba2+ or ...
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The ionic current underlying anomalous rectification in opener muscle fibers of crayfish was studied under two-electrode voltage clamp. Opener muscle fibers showed a mean resting potential (RP) of -64.8 mV and an input resistance of 0.4 M omega. Hyperpolarizing voltage command pulses from a holding potential (H) of -60 mV evoked an instantaneous voltage-independent linear current (IL) followed ...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy
سال: 1961
ISSN: 0021-4280
DOI: 10.2183/pjab1945.37.505